Hamburg beat league leaders St. Pauli in the derby, strengthening their own promotion hopes and allowing Darmstadt to go top.
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The home side slipped further towards the relegation zone, while the visitors are now only two points off the promotion places.
Heidenheim are still in the top six but they could only pick up a point from their long trip north.
Hannover followed up their impressive DFB Cup win over Borussia Mönchengladbach with a draw at home to fellow midtable club Dresden.
Official Bundesliga 2 transfer centre: Summer 2022
Every move in Germany's second division during the summer window...
Official Bundesliga transfer centre: Summer 2022
All the official ins and outs at your favourite Bundesliga club...
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The 10th season in the bevestor Virtual Bundesliga is approaching its climax: The VBL Grand Final by Bevestor on June 4th and 5th!