Following their elimination from the UEFA Champions League on Tuesday, Bayern will want to finish the domestic campaign on a high after losing both their last two league encounters, while Freiburg are scrapping for their lives at the foot of the table.
bundesliga.com looks ahead to Saturday's clash in the Black Forest...
For Freiburg, the stakes could not be higher. They need to win to remain in control of their own destiny going into the final weekend of the season. Bayern, meanwhile, have nothing quite as tangible to play for, but their dented pride after recent defeats in the league, DFB Cup and Champions League will ensure they take this trip seriously.
(groin) and (thigh) are doubts for Christian Streich, who will once again keep his cards close to his chest ahead of the game. 's omission was one of five changes made by the 49-year-old head coach against Hamburger SV last weekend, but the striker could return against his former club.
Bayern's lengthy injury list remains and with only two games of the season remaining, there is little point in rushing any of their sidelined stars back into the first-team fold. Goalkeeper is suspended after being sent off against FC Augsburg last time out, while (l.) is also serving a one-match suspension
was on target against Hamburg last weekend, surprisingly only for the third time this season. The Swiss international forward has had 48 shots on goal and set up a further 29 for his team-mates, but he has only two more games to improve on a meagre goal tally by his own standards.
He was the man Pep Guardiola wanted more than anybody when he arrived almost two years ago, and now his injury problems are behind him, (l.) is showing once again precisely why. Arguably one of the most comfortable players in world football on the ball, he provides the link between Bayern's defence and midfield, like a metronome dictating the pace of the game.
, forward: "We're going to have to run, play and fight from start to finish if we want to have a chance of getting anything against this Bayern. Above all, we're going to have to defend really well. That's the basis when you are playing against Bayern. We know that we can do all the rest."
, captain: "We've definitely had a good season. When you win the league for a third year in a row and reach two semi-finals, then you can definitely say you've had a good season. It's not something you can just take for granted."
Freiburg's last win came over a month ago - on 4 April - and they have drawn three and lost three since, missing several to pull away from the relegation zone in the process. Bayern ended a rare four-game losing streak by beating FC Barcelona on Tuesday, even if it was not enough to avoid elimination from Europe's premier club competition.
Freiburg's record against Bayern will not instil them with too much confidence - they have managed to beat them only three times in 31 Bundesliga encounters, drawing six and losing the other 22. One of those draws came at home last season, and that will be their benchmark on Saturday.
Freiburg: Bürki - Mujdza, Krmas, Mitrovic, Günter - Höfler, Darida - Schmid, Klaus - Guede, Mehmedi
Bayern: Neuer - Rafinha, Boateng, Benatia, Bernat - Thiago, Xabi Alonso - Lahm, Müller, Schweinsteiger - Götze