bundesliga.com has the pre-match lowdown from both camps ahead of the crunch clash at the Stadio Giuseppe Meazza...
It's a simple enough formula for Wolfsburg, who will definitely progress if they avoid defeat following last week's 3-1 first leg win on home turf. Inter will be desperate not to concede on the night, with a 2-0 win the ideal result for them. Any victory by a three-goal margin would also be enough to take the Italians through.
Roberto Mancini's preparations have been rocked by news of a thigh injury to former FC Bayern München winger Xherdan Shaqiri (r.), who misses out on Thursday night. Japanese defender Yuto Nagatomo is definitely unavailable, while Serbian centre-back Nemanja Vidic is a doubt through illness.
The Wolves will have to do without the services of towering centre-half (l.), who serves a mandatory one-match ban after picking up a yellow card last time out. Dieter Hecking has a ready-made replacement in Timm Klose, though, with midfielder Aaron Hunt the 50-year-old strategist's only other absentee.
Rodrigo Palacio showed his class with what could turn out to be a crucial away goal at the Volkswagen Arena. The diminutive Argentine frontman was also on target at the weekend, rescuing a point for the Nerazzurri in a 1-1 draw at home to relegation-threatened AC Cesena.
There's not a single thing Kevin De Bruyne can do wrong at the moment. After grabbing a brace and setting up Naldo's equaliser in last Thursday's reverse fixture, the in-form Belgian scored another and won a penalty, before laying on his 16th league assist of the season in the Wolves' Freiburg win. 'Purple patch' doesn't come close.
Mancini (head coach): "Wolfsburg are a good team - they've already shown why they're second in the Bundesliga. But if we put in a strong performance, we have a chance of reaching the next round."
(Wolfsburg centre-back): "They're going to try and put pressure on us from the word go, we'll have to be on our guard. We'll respect them, but we've got nothing to be scared of."
Internazionale have been struggling for form of late, the 2012 UEFA Champions League winners without a victory in their last four matches in all competitions. Wolfsburg, on the other hand, have lost just once in ten outings since the turn of the year (W8, D1).
De Bruyne (2nd r.) had a huge hand in Wolfsburg's first win in four attempts against Italian sides (W1, D1, L2) in last week's first leg. Their two previous trips to Italy ended in a 1-0 defeat and a 2-2 draw. Internazionale, meanwhile, have won only once in their last five home games against German opposition (SV Werder Bremen, 2010/11).
Inter: Carrizo - d'Ambrosio, Juan Jesus, Ranocchia, Santon - Medel, Guarin, Hernanes - Kovacic - Palacio, Icardi
Wolfsburg: Benaglio - Vieirinha, Klose, Knoche, Rodriguez - Luiz Gustavo, Guilavogui - Caligiuri, De Bruyne, Schürrle - Dost