Borussia can guarantee their participation in the knockout rounds of the competition with another victory against the side they dispatched 4-0 in Istanbul two weeks ago. bundesliga.com has all you need to know ahead of this potentially decisive encounter at the Signal Iduna Park...
To put their woeful league form to one side, Dortmund have been little short of brilliant in Europe. Three wins from three, nine goals scored and none conceded have put them within touching distance of the last 16. Win this game and their names are in the hat, although second-placed Arsenal FC could still pip them to Group D's top spot.
Jürgen Kopp lost another influential player to injury last weekend when Mats Hummels (pictured) was forced off with a foot injury in the 2-1 loss to FC Bayern München. Neven Subotic or Matthias Ginter will replace the 25-year-old but Oliver Kirch, Marcel Schmelzer and Nuri Sahin are all sidelined.
Galatasaray coach Cesare Prandelli is sweating on the fitness of combative midfielder Felipe Melo, who has been suffering with a thigh strain of late. Striker Burak Yilmaz (pictured) is definitely available but fellow forward Aydin Yilmaz is out with a foot problem.
When Marco Reus plays well, Dortmund usually play well. The 25-year-old Germany international was on the scoresheet against Bayern on Bundesliga Matchday 10 and was the best player on the pitch at the Türk Telekom Arena a fortnight ago, netting a sublime effort himself and assisting another for Pierre-Emerick Aubameyang.
Wesley Sneijder may have been overshadowed by Reus in the sides' first meeting, but the 109-time Dutch international still possesses a match-winning ability like few others. He scored two stunning long-range efforts to defeat rivals Fenerbahce SK in the local derby recently and BVB would do well to keep him shackled at all times.
Jürgen Klopp, BVB head coach: "We have an important game against Gladbach on Sunday, but now, and for 90 minutes tomorrow, we have to focus completely on Galatasaray."
Sebastian Kehl, BVB midfielder: "We don't have time to dwell on the league defeats. We'll try to approach this as a game that we'll enjoy and hopefully seal our place in the next round."
Dortmund cannot buy a win in the Bundesliga at present. Defeat in Munich was their fifth in a row on the home front and they are now in the bottom three, their lowest league position at this stage of a campaign since March 2007. Galatasaray, meanwhile, are top of the Turkish Super Lig after a 2-1 win at home to Kasimpasa AS last Friday.
Aside from BVB's crushing win on Matchday 3, the two teams have faced off four times in European competition. Borussia, as holders, won home and away in the group stages of the 1997/98 Champions League, while Galatasaray prevailed over two legs in the fourth round of the 1999/2000 UEFA Cup, which they went on to win.
Dortmund: Weidenfeller - Piszczek, Subotic, Sokratis, Durm - Bender, Gündogan - Aubameyang, Mkhitaryan, Reus - Immobile
Galatasaray: Muslera - Sabri, Semih, Chedjou, Alex Telles - Felipe Melo, Selcuk Inan - Hamit Altintop, Dzemaili, Sneijder - Burak Yilmaz