The Foals boast a 3-2 lead from last week's first leg, meaning they only need to avoid defeat to progress to the competition's group stages, the draw for which will be made at 12.00 GMT / 13.00 in Monaco on Thursday.
Max Kruse is still not yet fit enough to be involved because of a pelvis injury, although Christoph Kramer, who played on Saturday for the first time since the FIFA World Cup final, could be given a start. "He's come on a lot since winning the World Cup. He's louder in training," remarked coach Lucien Favre.
With his team needing to force the issue, Haris Duljevic could come into the starting line-up after finding the net from the bench in the first leg. Otherwise, head coach Abdulah Ibrakovic is expected to name an unchanged line-up from the first leg.
The two sides have met just once: in last week's first leg, which Borussia edged by a 3-2 scoreline. The star of the show was arguably Branimir Hrgota, who delivered on the promise he showed in pre-season, and in recent years, by bagging a brace.
Andre Hahn enjoyed a barnstorming start to his European career, scoring once and assisting another in last week's first leg. He was replaced with 15 minutes to go in the league at the weekend, but will be itching to help his new club rubber stamp their ticket to the group stages.
Creative midfielder Milos Stojcev was perhaps the Bosnians' standout performer in the first leg. Despite failing to trouble the scores, the former Sporting Kansas City man was a calming presence for FK and rarely conceded possession. Gladbach will look to prevent him orchestrating play from the middle of the park.
Lucien Favre: "We need a good performance to go through. Nothing is decided yet. Sarajevo are dangerous away from home."
Tony Jantschke: "We're grateful to be able to play in the Europa League and we'll give it everything to make sure we play at least six more games."
Gladbach needed an 89th-minute equaliser from World Cup winner Kramer to salvage a point from their opening-day encounter with VfB Stuttgart, while Sarajevo come into the game after a draw at the weekend in their domestic league.