At the same stage of last season's competition, the Bavarians took a 3-1 lead into the return leg at the Allianz Arena, only to scrape through to the quarter-finals on away goals after losing 2-0 to the Gunners in Munich.
'Have to play aggressively'
Guardiola is in no mood to let light lightning strike twice following his team's 2-0 victory in London last month. "We have to win this game. We have to forget about the first leg," said the Spaniard at Monday's pre-match press conference. "If we rest on our laurels and let Arsenal into the game, we'll get into trouble."
"We have to play aggressively, with and without the ball. I want to see my team fight for the right result," added the 43-year-old, whose team have scored 15 goals in their last three matches. "We're in the last 16 and we need to earn our place in the last eight. Arsenal's quality is always there to see. I know Arsene Wenger well and so do my players. They know what they have to do."
'We could lose again'
Midfielders Thomas Müller and Toni Kroos, who joined Guardiola at Monday's press conference, are determined to avoid a repeat of last season's narrow escape. "[That game] should be warning enough," said Kroos, who opened the scoring in Bayern's win at the Emirates Stadium. "It's important that we get to grips with their better players, like we did in London."
"It's possible that [we could lose] again," conceded Müller. Indeed, Bayern have already lost at home to English opposition in the Champions League this season, having slumped to a 3-2 defeat to Manchester City FC in December's final Group D encounter. "I think we've learned our lesson, though," admitted the 24-year-old. "I don't expect to lose again."
'Ready to fight'
As was the case at the Volkswagen Arena on Saturday, Guardiola has a full squad to choose from for the visit of Arsene Wenger's team. The Frenchman, who saw his side advance to the semi-finals of the English FA Cup at the weekend, is confident of overturning the first-leg deficit in Munich.
"We're ready to fight. We need to score three goals - even if they score, it doesn't change anything," said Wenger. "We have to take the initiative and try to score goals." Arsenal will have to do so without midfielder Jack Wilshere, however, after the England international suffered a hairline fracture in his left foot on Saturday. Keeper Wojciech Szczesny, meanwhile, is suspended following his red card in London three weeks ago.
Bayern München: Neuer - Rafinha, Boateng, Dante, Alaba - Lahm - Robben, Thiago, Kroos, Ribery - Müller (Mandzukic)
Arsenal: Fabianski - Sagna, Mertesacker, Koscielny, Gibbs - Arteta, Flamini - Santi Cazorla, Özil, Oxlade-Chamberlain (Podolski) - Giroud