Defeat would leave the Foals six points behind the nine-time French champions and still trailing Fenerbahce, irrespective of their result away to underdogs AEL Limassol.
"Looking at the table and considering it's a home game, there's we have to keep all three points here," said Borussia's Germany U-21 international Tony Jantschke. Marseille coach Elie Baup is equally aware of the significance of the game, claiming Fenerbahce as the favourites for the group: "It's important to play well here. Gladbach are our rivals for second place."
Following a perfect season start with six opening wins in Ligue 1, the visitors' form has dipped of late and they have only earned one point from the last three games and lost top spot after losing 1-0 to Troyes at the weekend. "We have to turn things around to get back our united front that was our strength before," said Baup. "As soon as you lose, it starts making things harder."
Domestic woes are something the hosts are all too familiar with themselves this term. Nine points from eight games leave the Rhineland club in 13th place in the Bundesliga, with the team especially struggling at the back. The 16 conceded goals so far are only eight less than Lucien Favre's side let in over the course of the entire 2011/12 campaign. "We have to turn things around by working even harder," said 22-year-old Jantschke. "We have to run for each other, fight and not shy away from a challenge."
Marseille's main dangerman Andre-Pierre Gignac will not be available against Mönchengladbach due to a foot injury. Nonetheless, Favre does not believe the striker's absence will give his charges much of an advantage, especially with the likes of Loic Remy and Andre Ayew in the side. "Marseille are a very athletic team. They have robust players and enormous quality."
Gladbach: ter Stegen - Jantschke, Stranzl, Dominguez, Daems - Nordtveit, Marx - Rupp, Xhaka, Arango - de Jong
Marseille: Mandanda - Abdallah, Fanni, Nkoulou, Morel - Kabore, Ben, Cheyrou - Amalfitano, Calbuena, Ayew