Germany now face a must-win game against Sweden on 23 June, and will likely have to beat South Korea in their final group outing to keep alive their dream of becoming the first nation since Brazil in 1962 to win back-to-back World Cups - but Werner insists the defending champions have no reason to panic
"Of course we can still win the World Cup," the RB Leipzig and Germany striker said. "We are Germany and we want to win every game. Things like this can happen, you can lose a game, but you have to show a reaction as quickly as possible and find the best way forward."
Hirving Lozano's first-half goal was the difference between Mexico and Germany in Moscow as the world champions fell to their first World Cup defeat since losing 1-0 to Spain in the 2010 semi-finals, and it's La Roja - the only team to lose their opener and go on to win the World Cup - who Werner hopes his side can emulate in Russia.
"It is better to lose the first game than the fourth or fifth," he said. "Spain lost their first match at the World Cup in South Africa [to Switzerland] and ended up being champions. Now what we have to do is win the next match against Sweden."
Germany head coach Joachim Löw is expected to make changes to his side for the game against Sweden, but Werner is unlikely to be one of them.
The 22-year-old has scored eight goals in 14 senior internationals to date, and scooped the Golden Boot at the 2017 FIFA Confederations Cup. He has hit 34 goals in his last two seasons in the Bundesliga.