James was the chief architect of a stunning first-half display from Bayern, scoring once and setting up another two as Jupp Heynckes’ men led 5-0 at the break before Robert Lewandowski completed his hat-trick late on in a Der Klassiker masterclass.
The crushing defeat of Dortmund, who lost for the first time in 13 league matches under new coach Peter Stöger, made up for the disappointment provoked by Schalke’s 2-0 defeat of Freiburg earlier in the day that meant Bayern could not clinch the title on Matchday 28.
Watch: James eyes Champions League success
With a 17-point lead over the Royal Blues with six games left, Jupp Heynckes’ men will claim their club’s 27th Bundesliga crown with victory at Augsburg next time out.
On Tuesday evening, James came off the bench in Seville to help set-up Bayern's equaliser in their Champions League quarter-final first leg, putting them on course to reach the last four of a competition he believes the Bavarians can win.
“We can do it. Why not?,” the Colombia international told bundesliga.com. “I think that is something we can think about, something we need to think about together, in tune. I think that is our joint dream. The club hasn’t been able to win it in the last few years and I believe that this year, we can dream about it.”