FC Schalke 04 could give new boy Yevhen Konoplyanka his first start since his arrival on loan from Sevilla, while FC Bayern München may give the exciting 19-year-old Renato Sanches his debut (kick-off: Friday, 20:30 CEST/19:30GMT).
The Portuguese midfielder, a star in his country’s UEFA Euro 2016 triumph, sat out Bayern’s 6-0 thrashing of Werder Bremen two weeks ago.
Schalke possible line-up: Fährmann - Caicara, Naldo, Höwedes, Baba - Geis, Bentaleb, Konoplyanka, Meyer - Huntelaar, Embolo
Absentees: Coke (knee ligaments), Uchida (Achilles)
Head coach: Markus Weinzierl
Bayern possible line-up: Neuer - Lahm, Martinez, Hummels, Alaba - Alonso, Thiago, Sanches - Müller, Ribery - Lewandowski
Absentees: Badstuber, Boateng, Robben (all fitness), Coman (ankle)
Head coach: Carlo Ancelotti