Bayer 04 Leverkusen defender Ömer Toprak has been ruled out for at least a week with a thigh injury.

The 26-year-old Turkey international, who only returned to action in Matchday 26's 1-0 win over Hamburger SV following three weeks on the sidelines, will miss Thursday's UEFA Europa League Round of 16 second leg against Villarreal CF and Sunday's clash with VfB Stuttgart in the Bundesliga.

Watch: Highlights from Leverkusen's win over Hamburg

Leverkusen lost 2-0 to Villarreal at the Estadio El Madrigal in last week's first leg, and currently sit three points outside the Bundesliga's coveted UEFA Champions League qualification places in seventh.