Borussia Dortmund's Marco Reus will be out of action for roughly a month due to injury, the club confirmed on Sunday, ruling him out of their crunch UEFA Champions League last-16 second leg against Benfica on Wednesday night.

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The attacking midfielder was withdrawn holding his left thigh in the 44th minute of BVB's 6-2 win against Bayer Leverkusen on Matchday 23. The club have since confirmed that Reus has suffered in injury to his left thigh, which will keep him out of action until early-April, meaning he will miss the visit of Benfica and make it a race against time for him to be fit for the season's second Klassiker against FC Bayern Munich.

Reus holds his left leg in pain. © imago / Thomas Bielefeld

"It's hit us hard," said Dortmund coach Thomas Tuchel. "Marco took a lot of responsibility today and was really up for it. He's been playing at an outstanding level for several weeks and is an important character on the field. That he's not going to be able to play on Wednesday is a major blow and overshadows today's win."

Dortmund trail 1-0 from the first leg in Lisbon, but warmed up for the visit of the Portuguese champions by comfortably seeing off Leverkusen thanks to goals from Ousmane Dembele, Pierre-Emerick Aubameyang (two), Christian Pulisic, Andre Schürrle and Raphael Guerreiro.

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Watch: Christian Pulisic discusses BVB's Matchday 23 success: