Official Fantasy Bundesliga Managers take note: bundesliga.com is on hand to provide likely line-ups as well as injury and suspension news ahead of Matchday 22.
Bayer 04 Leverkusen vs 1. FSV Mainz 05 (kick-off 15:30CET/14:30GMT).
With left-back Wendell suspended, Roger Schmidt could move Benjamin Henrichs h over to the left of defence, with Tin Jedvaj starting on the right. Lars Bender is a doubt, which leaves Charles Aranguiz and Julian Baumgartlinger both on standby, the former having deputised for Bender in Tuesday's UEFA Champions League loss against Club Atletico de Madrid. Kai Havertz – a big Fantasy Bundesliga earner on Matchday 21 – is holding off Kevin Volland for a place in support of Chicharito.
Watch: Leverkusen's 3-1 win in Augsburg, including Bundesliga goal 50,000:
Pablo De Blasis could be given a chance in the Mainz starting XI this weekend in place of Jairo Semperio, with the former's physical strength and presence preferred in such a fixture over the latter's technical qualities. Bojan Krkic and Robin Quaison are also alternatives, albeit most likely off the bench.
Watch: Highlights of Mainz's home defeat to Werder Bremen:
Leverkusen possible line-up: Leno - Jedvaj, Toprak, Dragovic, Henrichs - Aranguiz, Kampl - Bellarabi, Brandt - Havertz, Chicharito
Absentees: Wendell (suspended), Tah (thigh), Calhanoglu (suspended)
Coach: Roger Schmidt
Mainz possible line-up: Lössl - Donati, Bell, Ramalho, Bussmann - Gbamin, Latza - Frei - Öztunali, De Blasis - Cordoba
Absentees: Onisiwo (light training), Berggreen (light training)
Coach: Martin Schmidt