Süle, 22, was widely expected be used as back-up for Jerome Boateng and Mats Hummels following his summer 2017 move from Hoffenheim, but has already made 32 appearances in all competitions for the freshly recrowned Bundesliga champions, including 24 starts.
"When I look I Süle, he's going to be a superb player, world class," Heynckes said in an interview with kicker magazine after Bayern beat Augsburg 4-1 to wrap up their sixth successive Bundesliga title at the weekend.
"In a couple of years, he'll be the most sought-after central defender in Europe."
If Süle lives up to the hype - and there's every reason to believe he will - the nine-time Germany international will doubtless look back on his time working under the 72-year-old Heynckes as key to his development.
"Jupp talks a lot with the players, and lets them know how important they are to the team," Süle told www.t-online.de earlier this year.
"Personally I think it's great how much he asks of me, but he also has lot of faith in me. I know that because I'm playing a lot of games. That's really important for young players like me. I need minutes if I'm going to improve."