bundesliga.com rounds-up all the must-have pre-match information...
Dortmund's topsy-turvy season is currently on a knife edge: BVB are six points adrift of a European place and six ahead of the relegation zone. Win and optimism returns, while defeat could spark a nerve-wracking season finale. For Paderborn, meanwhile, nothing but a a victory will do to escape the drop zone.
BVB are without a handful of injured first team regulars, including Lukasz Piszczek (fitness), Nuri Sahin (ligaments), Neven Subotic (slipped disc), Sebastian Kehl (broken rib) and Oliver Kirch (ligaments). Marco Reus (l.) was only able to do individual exercises in training on Thursday and is a doubt for the game.
The visitors are not at full strength either, as set-piece specialist Alban Meha (elbow), former Dortmund striker Marvin Duksch (foot), Jens Wemmer (broken rib) and Thomas Bertels (fitness) are all sidelined.
Some of BVB's troubles this season have stemmed from wayward finishing - only eight teams have scored fewer goals thus far. With Pierre-Emerick Aubameyang set to lead the line once more, the hosts will be looking to the Gabon international to fire them to victory against the league's second-worst away side.
Only bottom club Hamburg have scored fewer than Paderborn's 25 goals this season, but the visitors must find the net here. Srdjan Lakic is the most likely candidate to do so, especially after he scored a well-taken header in the win against Augsburg last week.
Klopp (head coach): "Our first game against Paderborn didn't go as planned. They gave themselves a lifeline last week and I'm expecting them to have more confidence this time. The special thing about this game is that it's unbelievably important for both teams."
Andre Breitenreiter (head coach): "We'll have to run ourselves into the ground and force them into tackles. I'm anticipating a very intensive game because both teams want to win it. For us it's all about sending out a statement of our intent in the relegation battle."
Much will depend on how the Dortmund players react to Klopp's announcement that he's to leave the club at the end of the season. BVB go into the game on the back of two straight league defeats, while Paderborn will be buoyed by defeating Augsburg 2-1 last week.
These two have only met once before in the Bundesliga. On Matchday 12 Dortmund raced to a 2-0 lead at half-time, only to be pegged back to a 2-2 draw at the Benteler-Arena.
Dortmund: Weidenfeller - Durm, Sokratis, Hummels, Schmelzer - Bender, Gündogan - Blaszczykowski, Mkhitaryan, Reus - Aubameyang
Paderborn: Kruse - Heinloth, Rafa Lopez, Hünemeier, Hartherz - Ziegler - Koc, Bakalorz, Vrancic, Ouali - Lakic