Both clubs enter the final straight of the season harbouring ambitions of touring the continent in 2015/16. For Hoffenheim, a place in the UEFA Europa League is now the declared objective, while the Foals are desperate to finally punch their ticket to the UEFA Champions League.
bundesliga.com takes a closer look...
Were the season to end tomorrow, both Hoffenheim and Gladbach would be highly satisfied with what they have achieved. As many as eight games remain, however, meaning both can still improve on their current positions, or even climb a place or two between now and the end of the campaign.
Hoffenheim are without the suspended (r.), whose place in the defence is likely to be taken by . has served his suspension, however, and could return to Markus Gisdol's starting XI.
Lucien Favre could may opt to retain Raffael (l.) and Andre Hahn as his starting attackers after Matchday 26's running 2-0 win at FC Bayern München, which may mean German international (l.) remains on the bench. In terms of injuries, the coach has a squad has a clean bill of health.
(r.) took the plaudits for his inspiring displays for a Brazil side who see him as a key feature in their post-World Cup revolution this week. "Roberto's got an eye for goal and knows where his place is," said Brazil coach Dunga following the youngster's winning goal against Chile.
Fresh from penning a new contract, Patrick Herrmann (l.) has set his sights on earning his first international cap for Germany, and given the form he is in, few would begrudge him that either. "We're having a sensational season an so am I," said Herrmann, who has five goals in 2015.
Markus Gisdol: "We've got some big weeks coming up against top opponents. We're going to throw ourselves right into it and look to get the best we can out of it. We're all very ambitious and we've put ourselves in this great position, one that we've not been in for a long time. The Europa League would be something special for all of us."
Lucien Favre: "We've got a very interesting run of games to come over the next few weeks. Now we're fully focused on Hoffenheim and the challenges that come after. It's always hard to beat Hoffenheim. They're in the running for a place in Europe and have plenty of players who can win games by themselves."
Any team able to beat Bayern München in Munich must be in good form and Gladbach certainly are, with that 2-0 success taking them to ten points from their last four league matches. Hoffenheim have also been on song with three wins and two draws from their last six league outings, plus a win in the DFB Cup.
Still a relatively new fixture on the Bundesliga calendar, these sides have met 13 times with Hoffenheim leading with six wins to Gladbach's four. The Foals prevailed 3-1 in the reverse fixture, but they have yet to win in Sinsheim, picking up just two points from six visits.
Hoffenheim: Baumann - Beck, Abraham, Strobl, Kim - Rudy, Schwegler, Polanski - Volland, Firmino - Schipplock
Gladbach: Sommer - Jantschke, Stranzl, Dominguez, Wendt - Kramer, Xhaka - Herrmann, Hazard - Raffael - Kruse