bundesliga.com has all the team news and other pertinent match facts ahead of the encounter at Borussia Park.
Andre Hahn's (r.) Mönchengladbach are yet to lose this season while their guests are yet to win, giving the tie - on paper at least - the air of a foregone conclusion. Yet it is anything but, as Hamburg fought doggedly to keep record champions FC Bayern München at bay on Matchday 4 and will be keen to build on that performance to move up the table.
Coach Lucien Favre once again has every member of his first team squad available to him, although he has stated that changes will be made from the side that started against 1. FC Köln on Matchday 4. That could mean the likes of attacking midfielder (l.) and wingers Patrick Herrmann and Ibrahima Traore taking to the field from the off.
New HSV boss Josef Zinnbauer has not been so lucky on the personnel front, with Rafael van der Vaart (calf), Ivo Ilicevic (muscular complaints), Marcell Jansen, Slobodan Rajkovic and Maximilian Beister (all lacking fitness) set to miss out. Teenage Bayern loanee (r.) will also be absent after hurting his ribs in training.
A towering presence in midfield, also comes with an intimidating reputation as a 2014 FIFA World Cup winner. His tireless running provides ample cover for the Foals' defence, while his stats of 86 per cent passing accuracy and 57 per cent of tackles won show why he is one of the first names on Favre's teamsheet.
Striker may not have scored yet this season, but his role in the Hamburg side is pivotal. The 22-year-old's powerful physique unsettles defences and he is adept at bringing his team-mates into play. "He runs, grafts and holds balls up and is unbelievably important to the team," said Zinnbauer.
Lucien Favre (Gladbach coach, l.): "We didn't get ourselves in positions to outnumber [Köln] enough last weekend. We'll need to be better at that against Hamburg but again it won't be easy."
Zinnbauer (HSV coach): "[The Bundesliga's all-time leading scorer] Gerd Müller once said that you only strike if you shoot. That's very true and we want to start doing that against Gladbach."
Gladbach are unbeaten this term, drawing three and winning just the once - albeit a 4-1 thrashing of Schalke on Matchday 3. They don't concede many, with keeper Yann Sommer letting in just two so far. HSV began poorly by earning a solitary point from their first three games, but the Red Shorts looked very much rejuvenated under Zinnbauer last weekend.
Hamburg marginally have the upper hand in this fixture having won 36 of the 92 Bundesliga matches contested to date. Gladbach have triumphed 32 times, including both games last season, and have only lost once in their last six home matches against HSV.
Gladbach: Sommer - Korb, Stranzl, Jantschke, Wendt - Hazard, Kramer, Xhaka, Herrmann - Raffael, Kruse
Hamburg: Drobny - Diekmeier, Djourou, Westermann, Ostrzolek - Müller, Behrami, Holtby, Arslan, Stieber - Lasogga