bundesliga.com brings you the state of play going into the clash in northern Germany...
Getting the first win of the season will be the clear aim for both sides, Werder Bremen having drawn three while Schalke were held in two of their first four matches, including last weekend's dramatic 2-2 fightback at home to Eintracht Frankfurt.
An intestinal flu virus is doing the rounds in Bremen with , (pictured), Raphael Wolf and Felix Kroos all struck down over the past few days. Doubts remain over their inclusion, although the quartette were able to take part in the final pre-match training session. "They've all been weakened," said coach Robin Dutt.
Schalke coach Jens Keller will be without for this game and the weekend's Revier Derby after he was given a two-game suspension for his red card against Frankfurt. (pictured) will also have to sit out the trip to Bremen after he too was sent off at the weekend.
With three goals to his name already this season, is finally delivering on the potential Bremen saw in him when he signed from Wigan Athletic FC a year ago. The Argentinian has set himself the target of at least ten goals for the season and could be there as early as the midway stage, the way things are going.
was named bundesliga.com's Player of the Week on Matchday 4 with his penalty inspiring Schalke back from the brink against Frankfurt. It was the Cameroonian's second goal of the season, and his sixth successful spot-kick out of six in the top flight, underlining his great form since joining the Royal Blues in the summer.
"Of course I was delighted to score [last week against Augsburg], but my joy was dampened because we lost. Now we've got to put this behind us and move on."
"We need to get back to doing what we were doing in the second half of last season, and if one player is out, another has to come in and put in a good shift."
Bremen were unbeaten this season until the weekend's defeat to Augsburg, yet that result leaves the Green-Whites on just three points from a possible 12. Despite their impressive 1-1 draw in the UEFA Champions League at Chelsea, the Bundesliga form of Jens Keller's (pictured) Schalke side has also left a lot to be desired this term.
Bremen have beaten Schalke a total of 38 times, drawing 19 and losing 33. At the Weserstadion, meanwhile, Werder have only been beaten 11 times by the Royal Blues, although their last win dates back to April 2008. Three of Bremen's defeats have actually come in the past five seasons with Schalke winning six and drawing two of the last eight clashes.
Bremen: Wolf - Fritz, Prödl, Caldirola, Garcia - Junuzovic, Galvez - Bartels, Elia - di Santo, Selke
Schalke: Fährmann - Uchida, Ayhan, Neustädter, Fuchs - Höger, Aogo - Sam, Meyer, Choupo-Moting - Huntelaar