Frank made 215 Bundesliga appearances for VfB Stuttgart, Eintracht Braunschweig, Borussia Dortmund and 1. FC Köln between 1971 and 1982, scoring 89 goals.
As a coach at 1. FSV Mainz and MSV Duisburg, among others, he was one of the first German tacticians to employ a flat back four. Jürgen Klopp, who played under Frank at Mainz, described his former boss as his "mentor".
"For me, he was a revelation," Klopp told the regional newspaper Ruhr Nachrichten. "With our style of play, we were able to beat teams who were better than us. His great strength was that he always sent you into the game with a clear plan."
It was revealed in May that Wolfgang Frank had been diagnosed with a brain tumour.