Faltering Stuttgart face a Dortmund side looking to bounce back to winning ways.
Bayern's unbeaten record will be put to the test against high-flying Hertha.
Leverkusen and Schalke are both eyeing a top five berth.
Wolfsburg will be looking to make it back-to-back wins in Augsburg.
Gladbach are looking to go a ninth game unbeaten against struggling Hoffenheim.
Northern pride is at stake when Bremen play host to Hamburg.
The first Rhine-Main derby of the season pits Mainz against Frankfurt.
A Hannover side struggling at home welcome happy travellers Ingolstadt.
Köln have their sights set on the top six when they travel to Darmstadt.
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