Possible line-ups: Bayer 04 Leverkusen vs RB Leipzig
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Charles Aranguiz returned from international duty with Chile on Monday due in part to a suspension, but also because of an injury which makes him a doubt for Friday night. Roger Schmidt is optimistic he will be available, since he is unlikely to have Lars Bender available for a place in front of his defence. Schmidt has also welcomed a quartet back into training during the international break: Kevin Kampl, Ömer Toprak, Joel Pohjanpalo and Vladlen Yurchenko have all been given the green light to return.
Watch: Highlights of Leverkusen's Matchday 10 triumph over Darmstadt:
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Ralph Hasenhüttl had the luxury of 15 players in training for much of the international break, while regular goalkeeper Peter Gulacsi was also back in Leipzig early after playing only one of Hungary's two fixtures. Oliver Burke and Timo Werner both had a cold, but that is unlikely to rule either of them out on Friday.
Watch: Highlights of Leipzig's triumph over Mainz on Matchday 10:
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Leverkusen possible line-up: Leno - Henrichs, Tah, Toprak, Wendell - Aranguiz, Baumgartlinger - Kampl, Brandt - Hernandez, Volland
Absentees: Bellarabi (tendon)
Coach: Roger Schmidt
Leipzig possible line-up: Gulacsi - Ilsanker, Orban, Compper, Halstenberg - Demme, Keita - Sabitzer, Forsberg - Werner, Poulsen
Absentees: Klostermann (knee)
Coach: Ralph Hasenhüttl
Bayer 04 Leverkusen host RB Leipzig at the BayArena, with the game kicking off at 20:30CET/19:30GMT on 18 November.