bundesliga.com has all the must-know pre-match information ahead of the encounter at the Imtech Arena...
A chance to earn some much-needed points and to bank a healthy dose of confidence is on the line for both teams here, although more so for Josef Zinnbauer's Hamburg side, who are yet to score this term. Victory would boost Thomas Schaaf's Frankfurt outfit too though, as they have failed to win since Matchday 1.
Left-back Marcell Jansen has returned to full training but is unlikely to feature here due to a lack of fitness, while the quartet of Rafael van der Vaart, Maximilian Beister, Slobodan Rajkovic and Ivo Ilicevic are certain to miss out through injury. Bayern loanee could make his return, though.
First-choice keeper Kevin Trapp (pictured) faces a lengthy spell on the sidelines with an ankle injury, joining Nelson Valdez, Constant Djakpa, Johannes Flum and Sonny Kittel in the treatment room. Defender Carlos Zambrano is doubtful as he has been suffering from tonsilitis.
Finding the net has been a problem for Hamburg so far this term and if they are to do so here then their attacks need more pace and coherence. That thrusts into the spotlight as the team's creative hub, and much will depend on the 24-year-old's ability to pick a pass.
Hamburg have improved under Zinnbauer and are likely to put up a fight all over the pitch. To that end, Japan international will be crucial for the away side, with his strength in the tackle (60 per cent of all challenges won this season) required to protect the Eagles' back four.
Zinnbauer: Our players don't need a psychologist to be able to score. We just need to get our final ball into the box right and that's what we're working on.
Schaaf: We're facing a determined opponent who are keen to move up the table, but we need to focus on ourselves.
Things couldn't really be any worse for the hosts. They're currently bottom of the league and have not yet earned a or even managed to score this season. New coach Zinnbauer has instilled more fighting spirit, but up front they are too predictable at present. Frankfurt have been hit-and-miss are currently mid-table, having won one, drawn three and lost one.
If the past is anything to go by then HSV should win here, as they have earned maximum points from 41 of the 90 matches contested with the Eagles, even if both fixtures ended in draws (2-2 and 1-1) last season. On home soil Hamburg have triumphed 30 times from 45 matches, losing on just nine occasions.
Hamburg: Drobny - Diekmeier, Djourou, Westermann, Ostrzolek - Behrami, Arslan, Müller, Holtby, Stieber - Lasogga
Frankfurt: Wiedwald - Chandler, Zambrano, Russ, Oczipka - Medojevic, Ignjovski, Hasebe, Inui - Seferovic, Meier